Our research focuses on bone regeneration: allowing the body to regrow bone naturally where it’s needed, providing an alternative to painful and invasive bone grafts.
Over 20,000 hip and knee revision surgeries are performed in the UK each year (10% of all replacement surgeries).
One in two women and one in five men over 50 suffer a non-healing fracture due to conditions such as osteoporosis
Risk increases dramatically with age: 2% of women at 50 have osteoporosis, rising to over 25% at 80
“It was difficult watching Mum become increasingly immobile as her hip deteriorated. We all saw replacement as a light at the end of the tunnel but of course it was the start of a long, painful road to recovery. If she could have grown new bone, that would have been amazing.”Andrew
Treatment can be painful and fraught with problems
Non–healing fractures, bone defects caused by disease and tumour removal, hip and knee replacement revisions and spinal fusion surgery are currently treated with bone grafts. But the procedure can be fraught with problems, including a lack of available tissue, pain and non-healing at the donor site, disease transmission, rejection and inconsistent bone quality.
Building on our wound healing research RAFT is working to create a ‘scaffold’ that will encourage bone to regenerate – quite literally allowing new bone to grow wherever it’s needed within the body.
RAFT’s bone regeneration research scientists are working to create off-the-shelf artificial bone graft alternatives that will overcome the problems the procedure currently faces and provide an alternative to painful and invasive bone grafts, bringing effective treatment to millions. Read more on this research here.
For thousands of people, growing new healthy bone is just a dream – help us make it a reality!
RAFT’s bone regeneration research aims to eradicate the need for bone grafts and joint replacement revision surgery by creating a scaffold that will allow new bone to grow – where it’s needed within the body.
We need to raise funds to help take our research to human clinical trial so that we can provide an alternative to painful and invasive bone grafts and bring effective treatment to millions.
Our two current projects in this area call for funding of £517,000 over the period from 2017 to 2018, to fund:
- Research scientists
- Running costs: project management and administration
- Laboratory costs: testing & analysis, materials
- Presentation at relevant conferences
- Production of publications